For 70 years, the Office for the U.S.-Mexico Border has provided technical cooperation and support to local, state and federal health authorities in a binational response to health issues. Situated on the busiest and most traveled border in the world, the U.S.-Mexico Border Office is a binational geo-political system based on strong social, economic, cultural, and environmental connections governed by different policies, customs, and laws, said the chief of the field office for the United States-Mexico Border under the Pan American Health Organization/World Health Organization (PAHO/WHO), Dr. Maria Teresa Cerqueira, presented the context and health situation in the border region, on August 7, at PAHO Headquarters.