Born in Barbados, Sir George Alleyne obtained his degree in Medicine and Surgery from London University, England, in 1957 and his medical degree of the same house of high studies in 1965. From 1970 to 1993 he was member and president of the Advisory Committee on Medical Research of the Pan American Health Organization (PAHO). Queen Isabel II of the United Kingdom knighted him in 1990 in recognition of his services to medicine.

Alleyne was Director of PAHO/WHO from 1995 to 2003. In 2003, he was designated Director Emeritus of PAHO. From 2003 to 2010 he was special envoy of the United Nations Secretary General for HIV/AIDS in the Caribbean. In the video interview, Alleyne explains that the main global challenge is to reduce the unacceptable differences between the peoples of the world. He also considers that there are few things that a united Americas could not do.